New plasma biomarker to detect Alzheimer’s disease in Down syndrome individuals

Down Alzheimer - Plasma Markers - APOE

Plasma biomarkers Scientists worldwide are immersed in the race for accurate, non-invasive and accessible biomarkers to detect and diagnose Alzheimer’s Disease. To date, major scientific advances allowed the identification of several biomarkers in cerebrospinal fluid or using positron emission tomography (PET). Yet, these methods are either invasive or expensive and not easily accessible to all … Read more

Dr. Oriol Dols-Icardo, awarded by Fundación hna

Fundación hna - Oriol Dols-Icardo - Sant Pau Memory Unit

Research award by Fundación hna Fundación hna has awarded Dr. Oriol Dols-Icardo the prize of the first edition of the “Premio de Investigación Científica de Salud“. This is a competitive call for funding a research project on Amyotrophic Lateral Sclerosis (ALS), in which a total of 19 proposals have been submitted. The project funded by … Read more

Blood biomarkers are useful to detect Alzheimer’s disease

Marcadores Sangre - Alcolea - JNNP - Sant Pau Memory Unit

Blood biomarkers for Alzheimer’s disease Recent developments in blood markers have made possible to track the different pathophysiological processes that occur in Alzheimer’s disease through plasma analysis. Our study “Use of plasma biomarkers for AT (N) classification of neurodegenerative dementias” evaluates three of these markers and has recently been published in the Journal of Neurology, … Read more

What is the value of brain atrophy in frontotemporal dementia?

Atrophy - Illán-Gala - FTD - Sant Pau Memory Unit Barcelona

Atrophy and frontotemporal dementia The behavioral variant of frontotemporal dementia is a frequent cause of neurodegenerative dementia and the first cause of Frontotemporal Lobular Degeneration. Patients with the behavioral variant of frontotemporal dementia present a progressive personality change that begins years before diagnosis and can be confused with other neurodegenerative and psychiatric diseases. Identifying atrophy … Read more

Structural changes in the brain of patients with Alzheimer’s begin 20 years before the symptoms onset

Microestructura Alzheimer - Sant Pau Memory Unit - Barcelona

Structural brain changes in Alzheimer’s disease Brain alterations in Alzheimer’s disease patients begin years before symptoms appear and a clinical diagnosis can be made. The neuroimaging team in our group has developed a technique that measures the movement of water particles in the cerebral cortex and makes it possible to detect structural changes in the … Read more

Neurofilament and total tau in plasma for the diagnosis of frontotemporal dementia and Alzheimer’s

neurofilament - illan-gala - sant pau memory unit - barcelona

The Sant Pau Memory Unit publishes a new study in collaboration with the University of California San Francisco. The study examines the role of neurofilament light chain (NfL) and total tau levels in plasma for the diagnosis of frontotemporal dementia and Alzheimer’s disease. The work entitled “Plasma tau and neurofilament light in frontotemporal lobar degeneration … Read more