Welcome to the Memory Unit! We continue growing and adding talent to our team. We welcome our new team members and the professionals joining our Memory Unit during this period of training and collaboration. Visiting health professionals Professional Centre / Institution Activity Start End María Reverte Guardián Universitat Pompeu Fabra Bachelor’s Thesis: Biomedical Sciences 05/10/2026 … Read more
Introduction: What do we know about head injuries and neurodegenerative diseases? Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with repetitive head impacts and has been linked particularly to long-term participation in contact sports. It is characterized by the abnormal accumulation of a protein called tau in the brain and can only be definitively … Read more
Synaptic dysfunction is one of the earliest processes involved in Alzheimer’s disease (AD) and is closely associated with cognitive decline. However, currently available blood biomarkers primarily reflect other pathological processes, such as amyloid and tau pathology, neurodegeneration, or glial activation, while few biomarkers are available to detect early synaptic alterations through a blood sample. β-synuclein … Read more
Digital cognitive assessment and blood biomarkers: two complementary perspectives for assessing Alzheimer’s disease Blood-based biomarkers are making it easier to detect biological changes associated with Alzheimer’s disease through a simple blood test. However, on their own, they do not tell us whether a person has cognitive impairment or how it affects their functioning. A new … Read more
A strong link between the onset of Alzheimer’s and epileptic seizures In adults with Down syndrome, the risk of developing Alzheimer’s disease is particularly high due to genetic factors. In this study, we focused on analyzing the natural history of epilepsy in this population, observing how the appearance of the first symptoms of Alzheimer’s disease … Read more
White matter alterations are commonly observed in Alzheimer’s disease (AD) and reflect a convergence of several pathological processes, including myelin loss, axonal degeneration, and microvascular injury. Peak width of skeletonized mean diffusivity (PSMD) is a diffusion MRI–derived metric of diffuse white matter injury that has demonstrated high sensitivity to microstructural damage. However, the timing of … Read more