Overlapping microstructural changes in the brain of patients with ALS and frontotemporal dementia

ELA - DFT microestructura - Sant Pau Memory Unit - Barcelona

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) Until a few years ago, amyotrophic lateral sclerosis or ALS was considered a neurodegenerative disease that caused a progressive loss of strength with preservation of intellectual functions. However, in recent years we have learned that patients with ALS can frequently present with cognitive and personality changes that … Read more

Characterization of the transcriptome of the motor cortex in amyotrophic lateral sclerosis

Transcriptoma - ELA - Sant Pau Memory Unit - Barcelona

What is the transcriptome and why the motor cortex? The transcriptome is a set of tens of thousands of molecules called RNAs that have a key role in the formation of proteins and, therefore, in the response to pathological processes in the body. On the other hand, the motor cortex is the region of the … Read more

Markers for amyotrophic lateral sclerosis and frontotemporal degeneration

marcadors-ELA-DFT Neurology Sant Pau Memory Unit

The Department of Neurology of Hospital de Sant Pau has published in Neurology the article “CSF sAPPβ, YKL-40, and NfL along the ALS-FTD spectrum”. This study has been carried out by the Sant Pau Memory Unit and the Neuromuscular Disorders Unit of the Department of Neurology to investigate the clinical utility of cerebrospinal fluid markers in the … Read more

The Sant Pau Memory Unit awarded at the XXII Annual Meeting of the Catalan Society of Neurology

Societat Catalana de Neurologia

For the second consecutive year, Dr. Ignacio Illán Gala has received the Lluís Barraquer Bordas Prize in recognition for the best oral communication presented at the XXII Annual Meeting of the Catalan Society of Neurology held in Barcelona on May 22 and 23, 2018. In this communication, entitled “CSF levels of sAPPß and YKL-40 are related to … Read more