The diagnosis of Alzheimer’s disease and frontotemporal dementia or FTD can be hard. The use of biomarkers such as the levels of different proteins in the cerebrospinal fluid allows to improve the accuracy of the diagnosis. Specifically, protein levels related to the processing of amyloid precursor protein (APP) have been linked to cerebral amyloid protein … Read more Amyloid protein in patients with frontotemporal dementia
The Sant Pau Memory Unit has published a study that establishes reference values for a technique that allows the early detection of Alzheimer’s disease. This technique detects alterations in disease-related proteins in the cerebrospinal fluid of patients by means of an automated analysis. The study entitled “Agreement of Amyloid PET and CSF Biomarkers for Alzheimer’s … Read more The Sant Pau Memory Unit validates a technique for the early detection of Alzheimer’s
Biomarkers for the diagnosis of Alzheimer’s disease The characteristic symptoms of Alzheimer’s disease, such as progressive memory loss or other cognitive deficits and behavioral disorders, can make us suspect the diagnosis of this disease. This suspicion can be supported by the determination of biomarkers. Biomarkers measure the biological changes that occur in the brains of … Read more How do Alzheimer’s biomarkers change over time?
The Instituto de Salud Carlos III (Institute of Health Carlos III) has awarded subvention grants to four research projects submitted by the Sant Pau Memory Unit in the 2018 call for Health Research and Development Strategy in the modality of Proyectos de Investigación en Salud (Health Research Projects). This is an annual national competitive call that … Read more The Instituto de Salud Carlos III awards subvention grants to four projects of the Sant Pau Memory Unit
The Sant Pau Memory Unit has published in the Journal of Neurology, Neurosurgery and Psychiatry the results of a collaborative study with researchers from University of Pennsylvania (Penn FTD Center) that characterize two markers of frontotemporal degeneration. Frontotemporal degeneration Frontotemporal degeneration causes progressive behavioural changes and/or language impairment. Sometimes, it is associated with motor problems such as parkinsonism … Read more Our recent study in collaboration with University of Pennsylvania characterizes two markers of frontotemporal degeneration
The Department of Neurology of Hospital de Sant Pau has published in Neurology the article “CSF sAPPβ, YKL-40, and NfL along the ALS-FTD spectrum”. This study has been carried out by the Sant Pau Memory Unit and the Neuromuscular Disorders Unit of the Department of Neurology to investigate the clinical utility of cerebrospinal fluid markers in the … Read more Markers for amyotrophic lateral sclerosis and frontotemporal degeneration