Amyloid protein in patients with frontotemporal dementia

Illán-Gala, APP, frontotemporal - Sant Pau Memory Unit - Barcelona

The diagnosis of Alzheimer’s disease and frontotemporal dementia or FTD can be hard. The use of biomarkers such as the levels of different proteins in the cerebrospinal fluid allows to improve the accuracy of the diagnosis. Specifically, protein levels related to the processing of amyloid precursor protein (APP) have been linked to cerebral amyloid protein … Read more Amyloid protein in patients with frontotemporal dementia

Laura Cervera defends her doctoral thesis

CNV mitochondrial DNA and microRNA - Laura Cervera

Laura Cervera has defended her doctoral thesis today The thesis, entitled “Assessing the role of copy number variations, mitochondrial DNA and microRNAs in neurodegenerative disorders” has been directed by Dr. Jordi Clarimón and tutored by Dr. Alberto Lleó. In her work, Laura Cervera describes some markers of genetic origin that could be useful in neurodegenerative … Read more Laura Cervera defends her doctoral thesis

The Sant Pau Memory Unit validates a technique for the early detection of Alzheimer’s

Detección Precoz Alzheimer - Sant Pau Memory Unit - Barcelona

The Sant Pau Memory Unit has published a study that establishes reference values ​​for a technique that allows the early detection of Alzheimer’s disease. This technique detects alterations in disease-related proteins in the cerebrospinal fluid of patients by means of an automated analysis. The study entitled “Agreement of Amyloid PET and CSF Biomarkers for Alzheimer’s … Read more The Sant Pau Memory Unit validates a technique for the early detection of Alzheimer’s

How do Alzheimer’s biomarkers change over time?

Longitudinal Alzheimer Biomarkers - Sant Pau Memory Unit - Barcelona

Biomarkers for the diagnosis of Alzheimer’s disease The characteristic symptoms of Alzheimer’s disease, such as progressive memory loss or other cognitive deficits and behavioral disorders, can make us suspect the diagnosis of this disease. This suspicion can be supported by the determination of biomarkers. Biomarkers measure the biological changes that occur in the brains of … Read more How do Alzheimer’s biomarkers change over time?

Super-resolution is here for amyloid plaques

Amyloid Plaque - Sant Pau Mamory Unit - Barcelona

Non-fibrillar amyloid-β (Aβ) plaques are considered to be a critical component of Alzheimer’s disease. Characterization of these species comes mainly from studies in cellular or animal models, but there is little data in intact human samples due to the lack of adequate optical microscopic resolution to study these small structures. Marta Querol-Vilaseca in collaboration with … Read more Super-resolution is here for amyloid plaques

III Symposium of the DEGESCO Consortium

On May 16th, the III Symposium of the DEGESCO Consortium on Dementia Genetics will be held in Málaga, in the context of the VI Málaga Alzheimer Conference, sponsored by CIBERNED and the Andalusian Institute of Neuroscience. During the DEGESCO symposium, the ongoing projects of the consortium will be brought together and new proposals will be … Read more III Symposium of the DEGESCO Consortium