SPIN cohort: these are the details of the study protocol
The SPIN cohort The SPIN cohort (Sant Pau Initiative on Neurodegeneration) is helping us to learn many aspects about Alzheimer’s disease and other neurodegenerative diseases. A greater knowledge of these diseases brings us a little closer to an effective...
Amyloid protein in patients with frontotemporal dementia
The diagnosis of Alzheimer’s disease and frontotemporal dementia or FTD can be hard. The use of biomarkers such as the levels of different proteins in the cerebrospinal fluid allows to improve the accuracy of the diagnosis. Specifically, protein levels related...
Laura Cervera defends her doctoral thesis
Laura Cervera has defended her doctoral thesis today The thesis, entitled “Assessing the role of copy number variations, mitochondrial DNA and microRNAs in neurodegenerative disorders” has been directed by Dr. Jordi Clarimón and tutored by Dr. Alberto...
The Sant Pau Memory Unit validates a technique for the early detection of Alzheimer’s
The Sant Pau Memory Unit has published a study that establishes reference values for a technique that allows the early detection of Alzheimer’s disease. This technique detects alterations in disease-related proteins in the cerebrospinal fluid of patients by...
How do Alzheimer’s biomarkers change over time?
Biomarkers for the diagnosis of Alzheimer’s disease The characteristic symptoms of Alzheimer’s disease, such as progressive memory loss or other cognitive deficits and behavioral disorders, can make us suspect the diagnosis of this disease. This suspicion...
Super-resolution is here for amyloid plaques
Non-fibrillar amyloid-β (Aβ) plaques are considered to be a critical component of Alzheimer’s disease. Characterization of these species comes mainly from studies in cellular or animal models, but there is little data in intact human samples due to the lack of...
In our recent publication, we analyze cortical microstructure in frontotemporal dementia
The behavioral variant of frontotemporal dementia is a neurodegenerative syndrome characterized by a progressive personality change. Given that patients maintain their cognitive abilities relatively intact in the early stages of the disease, the diagnosis requires...
Ignacio Illán-Gala defends his doctoral thesis on frontotemporal degeneration
Today, Ignacio Illán-Gala has defended his Doctoral Thesis entitled “Pathophysiological and structural underpinnings of frontotemporal lobar degeneration: a multimodal biomarker study“, co-directed by Dr. Alberto Lleó and Dr. Juan Fortea. This exceptional...