Welcome to the team
Welcome! We would like to welcome the new members to the Memory Unit. Benjamin Buehner, is a german-canadian student who did his undergraduate degree in Biomedical Sciences at Queen’s University, in Canada. He is experienced on Sclerosis and...
Blood Biomarkers in Neurodegenerative Diseases: Implications for the Clinical Neurologist
Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and frontotemporal dementia, are a growing health concern worldwide, and their diagnosis and management are still challenging. However, recent advances in blood-based biomarkers...
Amyloid precursor protein βCTF accumulates in synapses in sporadic and genetic forms of Alzheimer’s disease
Amyloid precursor protein βCTF accumulates in synapses in sporadic and genetic forms of Alzheimer’s disease The main pathological features observed in a brain with Alzheimer’s disease (AD) are the accumulation of β-amyloid (Aβ) peptides in the form of plaques...
Bilingual Factors Associated with Cognitive Reserve and Linguistic Resilience in Hispanics with Primary Progressive Aphasia
Bilingual Factors Associated with Cognitive Reserve and Linguistic Resilience in Hispanics with Primary Progressive Aphasia Recent studies demonstrate that being bilingual can delay the onset of dementia by an average of 4-5 years. Stephanie Grasso (University of...
Enrichment of plasma-derived extracellular vesicles from astrocytes
Enrichment of plasma-derived extracellular vesicles from astrocytes Extracellular vesicles (EVs) are nanoparticles that are secreted by all cells in the body. EVs carries multiple cellular components, such as genetic material, proteins and lipid metabolites that often...
The Alzheimer’s Association has awarded 3 competitive projects to our unit
The Alzheimer’s Association has awarded 3 competitive projects to our unit. The funded projects have been the following: Role of synaptic miRNA and astrocyte miRNA delivery in Alzheimer’s disease (AARG-22-974373) led by Dr Olivia Belvin Alzheimer’s disease...
Myelin loss in C9orf72 hexanucleotide expansion carriers
Myelin loss in C9orf72 hexanucleotide expansion carriers The expansion of the intronic GGGGCC repeat (G4C2) in the C9orf72 gene is the most common genetic cause of Frontotemporal Dementia (FTD), Amyotrophic Lateral Sclerosis (ALS) and in the continuum of...
The link between Alzheimer’s disease and Down syndrome
The link between Alzheimer’s disease and Down syndrome People with Down syndrome are genetically predisposed to developing Alzheimer´s disease. The strong association between Alzheimer disease and Down syndrome has a genetic basis through a gene-dose effect of the...