Publication in The Lancet: natural history of Alzheimer’s disease in people with Down syndrome

Down - Sant Pau Memory Unit - The Lancet

Publication in The Lancet The Lancet, a world reference journal in Medicine, publishes the article “Clinical and Biomarker changes of Alzheimer’s disease in adults with Down syndrome: a cross-sectional study“, led by the Alzheimer Down Unit of the Hospital de Sant Pau and the Down Syndrome Catalan Foundation, in collaboration with researchers from the University … Read more

SPIN cohort: these are the details of the study protocol

SPIN cohort

The SPIN cohort The SPIN cohort (Sant Pau Initiative on Neurodegeneration) is helping us to learn many aspects about Alzheimer’s disease and other neurodegenerative diseases. A greater knowledge of these diseases brings us a little closer to an effective treatment. The participants of the SPIN cohort (patients and healthy volunteers) collaborate in the performance of … Read more

Amyloid protein in patients with frontotemporal dementia

Illán-Gala, APP, frontotemporal - Sant Pau Memory Unit - Barcelona

The diagnosis of Alzheimer’s disease and frontotemporal dementia or FTD can be hard. The use of biomarkers such as the levels of different proteins in the cerebrospinal fluid allows to improve the accuracy of the diagnosis. Specifically, protein levels related to the processing of amyloid precursor protein (APP) have been linked to cerebral amyloid protein … Read more

The Sant Pau Memory Unit validates a technique for the early detection of Alzheimer’s

Detección Precoz Alzheimer - Sant Pau Memory Unit - Barcelona

The Sant Pau Memory Unit has published a study that establishes reference values ​​for a technique that allows the early detection of Alzheimer’s disease. This technique detects alterations in disease-related proteins in the cerebrospinal fluid of patients by means of an automated analysis. The study entitled “Agreement of Amyloid PET and CSF Biomarkers for Alzheimer’s … Read more

In our recent publication, we analyze cortical microstructure in frontotemporal dementia

Brain - Illan - Sant Pau Memory Unit - Barcelona

The behavioral variant of frontotemporal dementia is a neurodegenerative syndrome characterized by a progressive personality change. Given that patients maintain their cognitive abilities relatively intact in the early stages of the disease, the diagnosis requires both a thorough clinical evaluation and biomarkers to support the diagnosis of a neurodegenerative disease. Ignacio Illán Gala and Victor … Read more

Is obesity a risk factor for Alzheimer’s disease?

Obesity and Alzheimer - Sant Pau Memory Unit - Alzheimer Research - Barcelona

Obesity and Alzheimer It has been established that middle-age obesity is a risk factor for Alzheimer’s disease, but the results from studies in older people are contradictory. Our recent study would explain the discrepancies on this topic. This work is the result of a collaborative effort between the Neuroimage team of the Sant Pau Memory … Read more