The diagnosis of Alzheimer’s disease and frontotemporal dementia or FTD can be hard. The use of biomarkers such as the levels of different proteins in the cerebrospinal fluid allows to improve the accuracy of the diagnosis. Specifically, protein levels related to the processing of amyloid precursor protein (APP) have been linked to cerebral amyloid protein … Read more Amyloid protein in patients with frontotemporal dementia
The Sant Pau Memory Unit has published a study that establishes reference values for a technique that allows the early detection of Alzheimer’s disease. This technique detects alterations in disease-related proteins in the cerebrospinal fluid of patients by means of an automated analysis. The study entitled “Agreement of Amyloid PET and CSF Biomarkers for Alzheimer’s … Read more The Sant Pau Memory Unit validates a technique for the early detection of Alzheimer’s
The behavioral variant of frontotemporal dementia is a neurodegenerative syndrome characterized by a progressive personality change. Given that patients maintain their cognitive abilities relatively intact in the early stages of the disease, the diagnosis requires both a thorough clinical evaluation and biomarkers to support the diagnosis of a neurodegenerative disease. Ignacio Illán Gala and Victor … Read more In our recent publication, we analyze cortical microstructure in frontotemporal dementia
Obesity and Alzheimer It has been established that middle-age obesity is a risk factor for Alzheimer’s disease, but the results from studies in older people are contradictory. Our recent study would explain the discrepancies on this topic. This work is the result of a collaborative effort between the Neuroimage team of the Sant Pau Memory … Read more Is obesity a risk factor for Alzheimer’s disease?
The Instituto de Salud Carlos III (Institute of Health Carlos III) has awarded subvention grants to four research projects submitted by the Sant Pau Memory Unit in the 2018 call for Health Research and Development Strategy in the modality of Proyectos de Investigación en Salud (Health Research Projects). This is an annual national competitive call that … Read more The Instituto de Salud Carlos III awards subvention grants to four projects of the Sant Pau Memory Unit
A recent study carried out at the Sant Pau Memory Unit in collaboration with the Endocrinology Unit of Hospital Clínic (Barcelona) suggests that unintentional weight loss in cognitively healthy subjects might be related with Alzheimer’s disease. Our work is focused on healthy individuals, in other words, without any sign of cognitive impairment. The study has … Read more Weight loss in healthy elderly might be a sign of preclinical Alzheimer’s disease