Neuroimage

Assessing the value of MRI for the diagnosis of tauopathies

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MRI and tauopathies Progressive supranuclear palsy (PSP) and Corticobasal Degeneration (CBD) are two subtypes of Frontotemporal Lobular Degeneration characterized by cerebral accumulation of tau protein (tauopathies). These diseases present classically with motor symptoms that include postural instability, difficulty in ocular movements, and limb control. However, in recent years it has been shown that they can … Read more

Victor Montal defends his Doctoral Thesis

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Víctor Montal Blancafort has presented today his Doctoral Thesis entitled “Complex neuroimaging changes in metabolite, cortical structures and regional vulnerabilities in the Alzheimer disease continuum“. The thesis, directed by Dr. Juan Fortea and supervised by Dr. Alberto Lleó, delves into new neuroimaging measures that help establishing the dynamic changes that occur throughout Alzheimer’s disease. Given … Read more

Jordi Pegueroles defends his Doctoral Thesis

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Jordi Pegueroles - Sant Pau Memory Unit - Barcelona

In January 18th 2022, Jordi Pegueroles Monllau presented  his doctoral thesis entitled “The role of biomarkers in the current classification systems for Alzheimer’s Disease“. The thesis has been supervised by Dr. Juan Fortea and tutored by Dr. Alberto Lleó. This work has focused on the accuracy of different biomarkers of Alzheimer’s disease and their definition … Read more

What is the value of brain atrophy in frontotemporal dementia?

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Atrophy - Illán-Gala - FTD - Sant Pau Memory Unit Barcelona

Atrophy and frontotemporal dementia The behavioral variant of frontotemporal dementia is a frequent cause of neurodegenerative dementia and the first cause of Frontotemporal Lobular Degeneration. Patients with the behavioral variant of frontotemporal dementia present a progressive personality change that begins years before diagnosis and can be confused with other neurodegenerative and psychiatric diseases. Identifying atrophy … Read more

Structural changes in the brain of patients with Alzheimer’s begin 20 years before the symptoms onset

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Microestructura Alzheimer - Sant Pau Memory Unit - Barcelona

Structural brain changes in Alzheimer’s disease Brain alterations in Alzheimer’s disease patients begin years before symptoms appear and a clinical diagnosis can be made. The neuroimaging team in our group has developed a technique that measures the movement of water particles in the cerebral cortex and makes it possible to detect structural changes in the … Read more

Publication in The Lancet: natural history of Alzheimer’s disease in people with Down syndrome

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Down - Sant Pau Memory Unit - The Lancet

Publication in The Lancet The Lancet, a world reference journal in Medicine, publishes the article “Clinical and Biomarker changes of Alzheimer’s disease in adults with Down syndrome: a cross-sectional study“, led by the Alzheimer Down Unit of the Hospital de Sant Pau and the Down Syndrome Catalan Foundation, in collaboration with researchers from the University … Read more