Overlapping microstructural changes in the brain of patients with ALS and frontotemporal dementia

ELA - DFT microestructura - Sant Pau Memory Unit - Barcelona

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) Until a few years ago, amyotrophic lateral sclerosis or ALS was considered a neurodegenerative disease that caused a progressive loss of strength with preservation of intellectual functions. However, in recent years we have learned that patients with ALS can frequently present with cognitive and personality changes that … Read more

Circular RNAs in Alzheimer and frontotemporal dementia

Circular RNAs in Alzheimer and frontotemporal - Cervera - Sant Pau Memory Unit

What are circular RNAs? RNAs are a type of molecules present in all human cells. They usually have a linear conformation. However, some species with a ring-like structure have recently been described and named “circular RNAs”, but little is known about their function. Recent studies in the field have reported changes in the levels of … Read more

Amyloid protein in patients with frontotemporal dementia

Illán-Gala, APP, frontotemporal - Sant Pau Memory Unit - Barcelona

The diagnosis of Alzheimer’s disease and frontotemporal dementia or FTD can be hard. The use of biomarkers such as the levels of different proteins in the cerebrospinal fluid allows to improve the accuracy of the diagnosis. Specifically, protein levels related to the processing of amyloid precursor protein (APP) have been linked to cerebral amyloid protein … Read more

In our recent publication, we analyze cortical microstructure in frontotemporal dementia

Brain - Illan - Sant Pau Memory Unit - Barcelona

The behavioral variant of frontotemporal dementia is a neurodegenerative syndrome characterized by a progressive personality change. Given that patients maintain their cognitive abilities relatively intact in the early stages of the disease, the diagnosis requires both a thorough clinical evaluation and biomarkers to support the diagnosis of a neurodegenerative disease. Ignacio Illán Gala and Victor … Read more

Ignacio Illán-Gala defends his doctoral thesis on frontotemporal degeneration

Tesis doctoral - Illán-Gala - Frontotemporal - Sant Pau Memory Unit - Barcelona

Today, Ignacio Illán-Gala has defended his Doctoral Thesis entitled “Pathophysiological and structural underpinnings of frontotemporal lobar degeneration: a multimodal biomarker study“, co-directed by Dr. Alberto Lleó and Dr. Juan Fortea. This exceptional work is the result of the investigation in frontotemporal degeneration from a clinical and physiopathological approach. In this thesis, Dr. Ignacio Illán-Gala has … Read more

Dr. Illán-Gala has been selected as an “Atlantic Fellow” in the GBHI program

GBHI - Global Brain Health Institute

Dr. Ignacio Illán-Gala has been selected as one of the “Atlantic Fellows” of the Global Brain Health Institute (GBHI) in 2019. The objective of this program, coordinated by the University of California San Francisco and Trinity College Dublin, is to promote brain health globally by training a network of future leaders in brain health. The … Read more