Genetics

Characterization of the transcriptome of the motor cortex in amyotrophic lateral sclerosis

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Transcriptoma - ELA - Sant Pau Memory Unit - Barcelona

What is the transcriptome and why the motor cortex? The transcriptome is a set of tens of thousands of molecules called RNAs that have a key role in the formation of proteins and, therefore, in the response to pathological processes in the body. On the other hand, the motor cortex is the region of the … Read more Characterization of the transcriptome of the motor cortex in amyotrophic lateral sclerosis

Circular RNAs in Alzheimer and frontotemporal dementia

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Circular RNAs in Alzheimer and frontotemporal - Cervera - Sant Pau Memory Unit

What are circular RNAs? RNAs are a type of molecules present in all human cells. They usually have a linear conformation. However, some species with a ring-like structure have recently been described and named “circular RNAs”, but little is known about their function. Recent studies in the field have reported changes in the levels of … Read more Circular RNAs in Alzheimer and frontotemporal dementia

Now available our review on genetics in neurodegenerative dementias

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Genetics - Clarimon - Sant Pau Memory Unit

Although there are other unmodifiable causes of dementia, the existence of family aggregation indicates that genetics play a role to a greater or lesser extent. In recent years, there have been numerous studies that have provided new information that helps to better understand the genetic component in neurodegenerative diseases. Our Research Group, together with researchers … Read more Now available our review on genetics in neurodegenerative dementias

SPIN cohort: these are the details of the study protocol

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SPIN cohort

The SPIN cohort The SPIN cohort (Sant Pau Initiative on Neurodegeneration) is helping us to learn many aspects about Alzheimer’s disease and other neurodegenerative diseases. A greater knowledge of these diseases brings us a little closer to an effective treatment. The participants of the SPIN cohort (patients and healthy volunteers) collaborate in the performance of … Read more SPIN cohort: these are the details of the study protocol

Laura Cervera defends her doctoral thesis

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CNV mitochondrial DNA and microRNA - Laura Cervera

Laura Cervera has defended her doctoral thesis today The thesis, entitled “Assessing the role of copy number variations, mitochondrial DNA and microRNAs in neurodegenerative disorders” has been directed by Dr. Jordi Clarimón and tutored by Dr. Alberto Lleó. In her work, Laura Cervera describes some markers of genetic origin that could be useful in neurodegenerative … Read more Laura Cervera defends her doctoral thesis

III Symposium of the DEGESCO Consortium

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On May 16th, the III Symposium of the DEGESCO Consortium on Dementia Genetics will be held in Málaga, in the context of the VI Málaga Alzheimer Conference, sponsored by CIBERNED and the Andalusian Institute of Neuroscience. During the DEGESCO symposium, the ongoing projects of the consortium will be brought together and new proposals will be … Read more III Symposium of the DEGESCO Consortium