The multidisciplinary nature of the Sant Pau Memory Unit has favored the development of translational research lines that aim to bridge the gap between bench and clinic. Consequently, many of the results from these research lines have an immediate impact on clinical practice. Biomarkers This research line is focused on the identification and characterization of … Read more
Sant Pau Initiative on Neurodegeneration 1. What is the SPIN cohort? The main objective of the SPIN cohort (Sant Pau Initiative on Neurodegeneration) is to widen our knowledge of neurodegenerative diseases such as Alzheimer’s disease, Lewy body dementia and frontotemporal lobe degeneration, through the study of biochemical and neuroimaging markers (also known as biomarkers). This … Read more
Our Molecular Genetics Unit is focused on understanding the genetic causes underlying neurodegenerative disorders, and developing new genetic-based biomarkers to aid in disease diagnosis and prognosis. To accomplish this, we use state-of-the-art genetic tools such as next-generation sequencing, ddPCR, etc. applied to patients that have been diagnosed and followed-up by our memory clinic team. We … Read more
The neuroimaging group, led by Dr. Alexandre Bejanin, is a multidisciplinary clinical and research team studying neurodegenerative disorders through a wide range of neuroimaging measures. The group has extensive experience with using structural magnetic resonance imaging (MRI), diffusion (DTI) and functional MRI (fMRI), but also positron emission tomography (PET) techniques to detect neurodegeneration and Alzheimer’s … Read more
What are clinical trials? Clinical trials are used to evaluate the safety and efficacy of new drugs. Trials are divided in four phases: Phase I: During this phase, a drug is tested for the first time in healthy volunteers having previously been assessed for safety and efficacy in laboratory animals. All participants at this stage … Read more
