Structural changes in the brain of patients with Alzheimer’s begin 20 years before the symptoms onset
Structural brain changes in Alzheimer’s disease Brain alterations in Alzheimer’s disease patients begin years before symptoms appear and a clinical diagnosis can be made. The neuroimaging team in our group has developed a technique that measures the...
Neurofilament and total tau in plasma for the diagnosis of frontotemporal dementia and Alzheimer’s
The Sant Pau Memory Unit publishes a new study in collaboration with the University of California San Francisco. The study examines the role of neurofilament light chain (NfL) and total tau levels in plasma for the diagnosis of frontotemporal dementia and...
Circular RNAs in Alzheimer and frontotemporal dementia
What are circular RNAs? RNAs are a type of molecules present in all human cells. They usually have a linear conformation. However, some species with a ring-like structure have recently been described and named “circular RNAs”, but little is known about their function....
Recommendations to protect people with Down syndrome against COVID-19
The coronavirus outbreak COVID-19, which has been listed as a pandemic by the World Health Organization, affects especially vulnerable people and those with previous illnesses. While there is still no evidence on how coronavirus COVID-19 disease affects people with...
International registry of people with Down syndrome and coronavirus
The Alzheimer-Down Unit (Catalan Down Syndrome Foundation and Hospital de la Santa Creu i Sant Pau) participates in an international registry of people with Down syndrome affected by the coronavirus COVID-19 infection. This registry is powered by the Scientific...
Estrella Morenas defends her Doctoral Thesis
Estrella Morenas has defended today her Doctoral Thesis entitled “Multimodal biomarkers studies in the continuum Dementia with Lewy bodies – Alzheimer’s disease“. The academical act of defense of her doctoral thesis has taken place at the...
Now available our review on genetics in neurodegenerative dementias
Although there are other unmodifiable causes of dementia, the existence of family aggregation indicates that genetics play a role to a greater or lesser extent. In recent years, there have been numerous studies that have provided new information that helps to better...
SPIN cohort: these are the details of the study protocol
The SPIN cohort The SPIN cohort (Sant Pau Initiative on Neurodegeneration) is helping us to learn many aspects about Alzheimer’s disease and other neurodegenerative diseases. A greater knowledge of these diseases brings us a little closer to an effective...