Synaptic Proteins VAMP-2 and SNAP-25 as Biomarkers in Dementia with Lewy Bodies

Dementia with Lewy bodies (DLB) is one of the leading causes of dementia, yet clear biomarkers for its diagnosis and monitoring are still lacking. The Lewy bodies in the brains of people with DLB are primarily composed of accumulations of the protein α-synuclein, which can cause synaptic dysfunction from the early stages of the disease. … Read more

IR Sant Pau to Lead Synapsing, an Innovative Horizon-Europe Programme Project to Advance the Diagnosis and Treatment of Psychiatric Disorders and Neurodegenerative Diseases

The Sant Pau Research Institute (IR Sant Pau) has been selected to coordinate the ambitious European project Synapsing, an unprecedented initiative funded with seven million euros by the European Union through the Horizon-Europe programme. This project, involving thirteen leading institutions in clinical research, neuroimaging, and social sciences from nine European countries, aims to revolutionise the … Read more

Characterization of white matter hyperintensities in Down syndrome

White matter hyperintensities (WMH) are one of the imaging biomarkers of small vessel disease of presumed vascular origin. These lesions can be shown as areas of increases signal on fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging. WMH are frequently found in the elderly population and in both sporadic and genetic forms of Alzheimer’s disease (AD). … Read more

Microbleeds in individuals with Down Syndrome: Implications for Alzheimer’s disease treatment

Anti-amyloid drugs have emerged as a promising treatment for Alzheimer’s disease. However, these treatments can potentially cause cerebral microbleeds – small brain bleeds that may occur when amyloid is cleared from blood vessels. Understanding the natural history of these microbleeds is crucial for safe patient treatment and monitoring. This study, published in Neurology, provides key … Read more

Awarded with the SEN 2023 Prizes

Dr. Juan Fortea Ormaechea, director of the Memory Unit at Sant Pau Hospital, has been awarded the Scientific Modality Prize in the Alzheimer’s category during the Institutional Act of the Spanish Society of Neurology (SEN), held on June 6, 2024, at the Fonseca College of Santiago de Compostela. This prestigious recognition underscores Dr. Fortea’s world-class … Read more

International Nurses Day

Infermeres Unitat de Memòria

Today we celebrate International Nurses Day. Nursing is an essential profession within society. As nurses, we care for and provide support to people at all stages of their life. We are responsible for promoting health and overseeing it, with the patient at the center of our activities. Particularly, the nurses at the Memory Unit of … Read more