Biomarkers

Our recent study in collaboration with University of Pennsylvania characterizes two markers of frontotemporal degeneration

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JNNP- Alcolea et al - Sant Pau Memory Unit

The Sant Pau Memory Unit has published in the Journal of Neurology, Neurosurgery and Psychiatry the results of a collaborative study with researchers from University of Pennsylvania (Penn FTD Center) that characterize two markers of frontotemporal degeneration. Frontotemporal degeneration Frontotemporal degeneration causes progressive behavioural changes and/or language impairment. Sometimes, it is associated with motor problems such as parkinsonism … Read more

Markers for amyotrophic lateral sclerosis and frontotemporal degeneration

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marcadors-ELA-DFT Neurology Sant Pau Memory Unit

The Department of Neurology of Hospital de Sant Pau has published in Neurology the article “CSF sAPPβ, YKL-40, and NfL along the ALS-FTD spectrum”. This study has been carried out by the Sant Pau Memory Unit and the Neuromuscular Disorders Unit of the Department of Neurology to investigate the clinical utility of cerebrospinal fluid markers in the … Read more

A blood biomarker can detect Alzheimer’s disease in adults with Down syndrome

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Blood and CSF biomarkers in Down Syndrome - Sant Pau Memory Unit - Alzheimer Research - Barcelona

The Alzheimer – Down Unit, that comprises researchers from the Sant Pau Memory Unit of the Neurology Service at Hospital de la Santa Creu i Sant Pau and the Fundació Catalana Síndrome de Down, has published the results of a study of biomarkers in blood and cerebrospinal fluid of adults with Down syndrome in the … Read more

Publication: Challenges associated with biomarker-based classification systems

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Biomarker-based classification systems - Sant Pau Memory Unit - Barcelona - Alzheimer

The Sant Pau Memory Unit, in collaboration with researchers from the Hospital Clínic (Barcelona), ​​the Massachusetts General Hospital (Boston, USA) and the New York University School of Medicine (New York, USA) has recently published a paper in the journal Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring entitled “Challenges associated with biomarker-based classification systems for Alzheimer’s … Read more

A novel approach to identify neuropathological Frontotemporal Lobar Degeneration subtypes

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Sant Pau Memory Unit - Frontotemporal Degeneration - Biomarkers Research - Barcelona

Doctors Alberto Lleó and Ignacio Illán from the Sant Pau Memory Unit have recently published a work in the prestigious journal JAMA Neurology in collaboration with the University of Pennsylvania and the Penn Frontotemporal Degeneration Center (Philadelphia, USA). This work entitled “A two-step algorithm for the selection of neuropathological Frontotemporal Lobar Degeneration subtypes” tackle a crucial issue … Read more

Weight loss in healthy elderly might be a sign of preclinical Alzheimer’s disease

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Pèrdua de pes i alzheimer

A recent study carried out at the Sant Pau Memory Unit in collaboration with the Endocrinology Unit of Hospital Clínic (Barcelona) suggests that unintentional weight loss in cognitively healthy subjects might be related with Alzheimer’s disease. Our work is focused on healthy individuals, in other words, without any sign of cognitive impairment. The study has … Read more