Biomarker-based classification systems - Sant Pau Memory Unit - Barcelona - Alzheimer

Publication: Challenges associated with biomarker-based classification systems

The Sant Pau Memory Unit, in collaboration with researchers from the Hospital Clínic (Barcelona), ​​the Massachusetts General Hospital (Boston, USA) and the New York University School of Medicine (New York, USA) has recently published a paper in the journal Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring entitled “Challenges associated with biomarker-based classification systems for Alzheimer’s disease“.

In this paper, the authors underwent a critical appraisal of the A / T / N classification system proposed by Jack and colleagues. This is a relevant study since it emphasizes the limitations of exchanging biomarkers from different modalities (biomarkers in cerebrospinal fluid, nuclear medicine and magnetic resonance) for the classification of patients with Alzheimer’s disease. These limitations should be taken into account by the scientific community when updating the diagnostic criteria for Alzheimer’s disease expected by the end of 2018.

In this study, we used data from ADNI (Alzheimer’s Disease Neuroimaging initiative).

At the Sant Pau Memory Unit, we are very happy with this contribution and we hope to continue collaborating to further advance in the improvement of the diagnosis and treatment of Alzheimer’s disease.

Biomarker-based classification systems - Sant Pau Memory Unit - Barcelona - Alzheimer

More details on this publication can be found here:

Challenges associated with biomarker-based classification systems for Alzheimer’s disease. Illán-Gala I, Pegueroles J et al. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring

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