How do Alzheimer’s biomarkers change over time?

Longitudinal Alzheimer Biomarkers - Sant Pau Memory Unit - Barcelona

Biomarkers for the diagnosis of Alzheimer’s disease The characteristic symptoms of Alzheimer’s disease, such as progressive memory loss or other cognitive deficits and behavioral disorders, can make us suspect the diagnosis of this disease. This suspicion can be supported by the determination of biomarkers. Biomarkers measure the biological changes that occur in the brains of … Read more

In our recent publication, we analyze cortical microstructure in frontotemporal dementia

Brain - Illan - Sant Pau Memory Unit - Barcelona

The behavioral variant of frontotemporal dementia is a neurodegenerative syndrome characterized by a progressive personality change. Given that patients maintain their cognitive abilities relatively intact in the early stages of the disease, the diagnosis requires both a thorough clinical evaluation and biomarkers to support the diagnosis of a neurodegenerative disease. Ignacio Illán Gala and Victor … Read more

Markers for amyotrophic lateral sclerosis and frontotemporal degeneration

marcadors-ELA-DFT Neurology Sant Pau Memory Unit

The Department of Neurology of Hospital de Sant Pau has published in Neurology the article “CSF sAPPβ, YKL-40, and NfL along the ALS-FTD spectrum”. This study has been carried out by the Sant Pau Memory Unit and the Neuromuscular Disorders Unit of the Department of Neurology to investigate the clinical utility of cerebrospinal fluid markers in the … Read more

A blood biomarker can detect Alzheimer’s disease in adults with Down syndrome

Blood and CSF biomarkers in Down Syndrome - Sant Pau Memory Unit - Alzheimer Research - Barcelona

The Alzheimer – Down Unit, that comprises researchers from the Sant Pau Memory Unit of the Neurology Service at Hospital de la Santa Creu i Sant Pau and the Fundació Catalana Síndrome de Down, has published the results of a study of biomarkers in blood and cerebrospinal fluid of adults with Down syndrome in the … Read more

The Sant Pau Memory Unit in the AAIC 2018 – Chicago

Sant Pau Memory Unit - AAIC 2018 Chicago

The Sant Pau Memory Unit attended the annual Alzheimer’s Association International Conference (AAIC 2018) that was held in Chicago between July 22nd and 26th 2018. This conference, the largest dedicated to Alzheimer’s disease, gathers researchers from all over the world that share their knowledge and advances in the field. Here is the list of communications … Read more

Three well-differentiated clinical subtypes within dementia with Lewy bodies

Lewy Body profiles - Morenas-Rodriguez - Sant Pau Memory Unit - Barcelona

Dementia with Lewy bodies is a disease with a large clinical heterogeneity in which both symptoms and evolution can vary widely among patients. This clinical heterogeneity is linked to the great neuropathological variability found in autopsy. The Sant Pau Memory Unit of Hospital Sant Pau is a pioneer in the publication of the first study … Read more