Association of plasma phosphorylated tau 217 with clinical deterioration across Alzheimer disease stages
Blood biomarkers have become a key tool for diagnosing Alzheimer’s disease in a more accessible way. While plasma p-tau217 is already established as a strong diagnostic marker, little was known about its ability to predict how the disease progresses across different...
On the complexity of biomarker-driven diagnoses of Alzheimer’s disease
New biomarker-centric diagnostic frameworks for Alzheimer’s disease promise earlier detection but risk over-medicalising people who may never decline. Grasso, Santos-Santos and Clark contend that amyloid-β or phosphorylated-tau positivity in cognitively normal adults...
IR Sant Pau to Lead Synapsing, an Innovative Horizon-Europe Programme Project to Advance the Diagnosis and Treatment of Psychiatric Disorders and Neurodegenerative Diseases
The Sant Pau Research Institute (IR Sant Pau) has been selected to coordinate the ambitious European project Synapsing, an unprecedented initiative funded with seven million euros by the European Union through the Horizon-Europe programme. This project, involving...
Characterization of white matter hyperintensities in Down syndrome
White matter hyperintensities (WMH) are one of the imaging biomarkers of small vessel disease of presumed vascular origin. These lesions can be shown as areas of increases signal on fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging. WMH are...
Microbleeds in individuals with Down Syndrome: Implications for Alzheimer’s disease treatment
Anti-amyloid drugs have emerged as a promising treatment for Alzheimer’s disease. However, these treatments can potentially cause cerebral microbleeds – small brain bleeds that may occur when amyloid is cleared from blood vessels. Understanding the natural...
Awarded with the SEN 2023 Prizes
Dr. Juan Fortea Ormaechea, director of the Memory Unit at Sant Pau Hospital, has been awarded the Scientific Modality Prize in the Alzheimer’s category during the Institutional Act of the Spanish Society of Neurology (SEN), held on June 6, 2024, at the Fonseca College...
International Nurses Day
Today we celebrate International Nurses Day. Nursing is an essential profession within society. As nurses, we care for and provide support to people at all stages of their life. We are responsible for promoting health and overseeing it, with the patient at the center...
Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum
“Clinical dimensions along the nonfluent variant primary progressive aphasia spectrum” Dr. Ignacio Illán Gala is a Neurologist at the memory unit of the Hospital de la Santa Creu i Sant Pau. He currently leads the research group focused on the...