Martí Colom-Cadena - Doctoral Thesis - Sant Pau Memory Unit - Alzheimer Research - Barcelona

Martí Colom-Cadena receives the Doctoral Thesis Extraordinary Award

Dr. Martí Colom-Cadena has received the Extraordinary Award for his doctoral thesis in Biomedicine entitled “Neuropathology of Lewy body diseases: confluence of multiple pathologies and role of synaptic phospho-alpha-synuclein“, defended at the University of Barcelona in June 2017.

Martí Colom-Cadena - Doctoral Thesis Extraordinary Award - Sant Pau Memory Unit - Alzheimer Research - Barcelona

In his doctoral thesis, jointly directed by Dr. Alberto Lleó and Dr. Ellen Gelpí and tutored by Dr. Isidre Ferrer, Dr. Colom-Cadena applied a novel technique of microscopy, “Array tomography, based on 70 nanometer-wide serial cut-offs, to study protein deposits and their relationship with the synapses in Lewy bodies diseases.

The results of his work, confirm that in dementia with Lewy bodies, characterized by alpha-synuclein deposits, is common the presence of co-pathologies, that is, accumulation of other proteins in the brain. It also describes a correlation between beta-amyloid and alpha-synuclein aggregates, suggesting a local synergy between them.

Currently, Dr. Colom-Cadena courses a postdoctoral fellowship at the Centre for Discovery of Brain Sciences at the University of Edinburgh.

Congratulations!

More information:

Teseo: Colom-Cadena M. Neuropathology of Lewy body diseases: confluence of multiple pathologies and role of synaptic phospho-alpha-synuclein. 2017

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