What does the health plan of the Alzheimer Down Unit consist of? The Alzheimer-Down Unit’s Health Plan is designed to provide medical and cognitive monitoring for adults with Down syndrome, with the goal of detecting potential changes related to Alzheimer’s disease at an early stage and providing specialized care. People with Down syndrome are at … Read more
In parallel with the care plan, the Alzheimer Down Unit developed a research program, the “Down Alzheimer Barcelona Neuroimaging Initiative” (DABNI), with the aim of studying the natural history of Alzheimer’s disease in adults with Down syndrome. It is an intensive study of biomarkers (a biomarker is a biological indicator that can be measured and … Read more
On World Alzheimer’s Day, the aim is to raise awareness about this incurable neurodegenerative disease that primarily affects elderly individuals. However, this year, Hospital de Sant Pau has shifted its attention to a particularly vulnerable group: individuals with Down syndrome. Alzheimer’s is characterized by cognitive decline and behavioral disturbances, with recent memory loss being one … Read more
Synaptic Tau Oligomers in Alzheimer’s Disease – A Possible Culprit in the Spread of Tau Pathology throughout the Brain Alzheimer’s disease is considered one of the most common causes of dementia in older individuals. Among the neuropathological features of Alzheimer’s disease (AD), the synaptic loss is the primary correlate of cognitive decline, and the … Read more
Cross-sectional versus longitudinal cognitive assessments for the diagnosis of symptomatic Alzheimer’s disease in adults with Down syndrome Individuals with Down syndrome are at a high risk of developing the clinical symptoms of Alzheimer’s disease in old age due to the triplicating of chromosome 21. However, the clinical diagnosis of this disease is challenging, mainly due … Read more
Alzheimer’s Disease, Down Syndrome and GFAP People with Down syndrome are at higher risk of developing Alzheimer’s disease than the general population. In fact, by the age of 70, more than 95% of people with Down syndrome will develop Alzheimer’s disease, which is the leading cause of death in this population. This strong association is … Read more