List of most recent publications led by the Sant Pau Memory Unit:
- The predictive power of neuropsychological measures in MCI: early detection of dementia conversion. Padilla, C, Zsadanyi, SE, Aragón, I et al. Front Aging Neurosci 2026PMID:42404240
- Clinical Impact and Prognostic Value of Alzheimer Disease Biomarkers in the Very Old. Ceriello, C, Torres, OH, Rubio-Guerra, S et al. Neurology 2026PMID:42308436
- Peak width of skeletonized mean diffusivity reveals early and multifactorial white matter injury across sporadic and Down syndrome-associated Alzheimer's disease. Morcillo-Nieto, AO, Franquesa-Mullerat, M, Zsadanyi, SE et al. Alzheimers Dement 2026PMID:42212383
- A Clinician View of the EMA Explanation of the Approval of Amyloid-Targeting Therapies. Jessen, F, Fortea, J Lancet Reg Health Eur 2026PMID:42180984
- Characterizing circadian rest-activity rhythm patterns across Alzheimer's disease continuum in Down syndrome. Giménez, S, Vaqué-Alcázar, L, Clos, S et al. Alzheimers Dement 2026PMID:42056071
- Evidence for bilingualism as a cognitive reserve factor in biomarker-confirmed Alzheimer's disease. Grasso, SM, Bao, W, Marqués-Kiderle, SK et al. medRxiv 2026PMID:41959833
- Amyloid-linked versus age-driven copathologies in Alzheimer's dementia: differential associations with APOE ε4. Rodríguez-Baz, Í, Vaqué-Alcázar, L, Maure-Blesa, L et al. Res Sq 2026PMID:41890856
- Impaired semantic word learning in primary progressive aphasia. Olivé, G, Cardona, G, Porto, MF et al. Brain Struct Funct 2026PMID:41882244
- Bilingualism's protective effects in Alzheimer's disease: Mechanisms of resilience and resistance. Bao, W, Grasso, SM, Sala, I et al. medRxiv 2026PMID:41757199
- Temporal dynamics of white matter hyperintensities related to Alzheimer's disease in adults with Down syndrome. Morcillo-Nieto, AO, Rozalem-Aranha, M, Maure-Blesa, L et al. Alzheimers Dement 2026PMID:41639041
- Potential role of MRI to optimize clinical trial design for progressive supranuclear palsy and corticobasal degeneration. García-Castro, J, VandeVrede, L, Donohue, MC et al. J Prev Alzheimers Dis 2026PMID:41581260
- Development of amyloid-negative neuropsychological norms using GAMLSS. Rubio-Guerra, S, Sánchez-Saudinós, MB, Sala, I et al. Alzheimers Dement (Amst) 2025PMID:41383879
- Amyloid-negative neuropsychological norms: Added value in the era of biomarkers and disease-modifying therapies. Rubio-Guerra, S, Sala, I, Sánchez-Saudinós, MB et al. Alzheimers Dement (Amst) 2025PMID:41383878
- Sleep-related changes in astrocytic biomarkers are modulated by APOE ε4 genotype in cognitively unimpaired adults. Zhu, N, Altuna, M, Arranz, J et al. Brain Commun 2025PMID:41268178
- Generational effects in Down syndrome: Enriched environment enhances functionality without reducing Alzheimer's disease risk. Vaqué-Alcázar, L, Videla, L, Benejam, B et al. Alzheimers Dement 2025PMID:41041908
- Study of brain perfusion in adults with Down syndrome along the Alzheimer's disease continuum. Franquesa-Mullerat, M, Morcillo-Nieto, AO, Arriola-Infante, JE et al. Alzheimers Dement 2025PMID:40968330
- Prospective evaluation of plasma pTau217 stability for the detection of Alzheimer's disease in a tertiary memory clinic. Arranz, J, Ferrer, R, Zhu, N et al. Alzheimers Res Ther 2025PMID:40618130
- Impact of Alzheimer's disease on sleep in adults with Down syndrome. Giménez, S, Vaqué-Alcázar, L, Zhu, N et al. Alzheimers Dement 2025PMID:40604343
- Discrepancies in assessing intellectual disability levels in adults with Down syndrome: Implications for dementia diagnosis. Soriano, LDH, Sandkühler, K, Videla, L et al. Alzheimers Dement 2025PMID:40528393
- The Down Alzheimer Barcelona Neuroimaging Initiative (DABNI) and its contributions to understanding Alzheimer's disease in Down syndrome: A decade of discovery. Videla, L, Benejam, B, Barroeta, I et al. Alzheimers Dement 2025PMID:40528282
- Cargo of small extracellular vesicles from neuronal origin shows progression of dementia in individuals with Down syndrome. Ledreux, A, Carmona-Iragui, M, Videla, L et al. Alzheimers Dement 2025PMID:40524460
- Association of Plasma Phosphorylated Tau 217 With Clinical Deterioration Across Alzheimer Disease Stages. Selma-Gonzalez, J, Rubio-Guerra, S, García-Castro, J et al. Neurology 2025PMID:40472304
- The history of Down syndrome-associated Alzheimer's disease; past, present, and future. Maure-Blesa, L, Carmona-Iragui, M, Lott, I et al. Alzheimers Dement 2025PMID:40469048
- Sex differences in the executive and behavioral reserve of autosomal dominant frontotemporal dementia. Garcia Castro, J, Rubio-Guerra, S, Casaletto, KB et al. Alzheimers Dement 2025PMID:40277045
- Nerve growth factor precursor alterations in neuron-derived extracellular vesicles from individuals with Down syndrome along the Alzheimer's disease continuum. Valle-Tamayo, N, Aranha, MR, Pérez-González, R et al. Alzheimers Dement 2025PMID:40257051
- A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration. Rubio-Guerra, S, Bernal, S, Almenta, D et al. Ann Clin Transl Neurol 2025PMID:40244880
- Medial temporal lobe atrophy in Down syndrome along the Alzheimer's disease continuum. Buehner, BJ, Morcillo-Nieto, AO, Zsadanyi, SE et al. Brain 2025PMID:40243675
- Sex-related differences in genetically determined Alzheimer's disease. Del Hoyo Soriano, L, Wagemann, O, Bejanin, A et al. Front Aging Neurosci 2025PMID:40103931
- Regional Brain Metabolism across the Alzheimer's Disease Continuum in Down Syndrome. Arriola-Infante, JE, Morcillo-Nieto, AO, Zsadanyi, SE et al. Ann Neurol 2025PMID:40084922
- Enhancing Lateral Resolution Using Two-Colour Direct Stochastic Optical Reconstruction Microscopy to Unravel Synaptic Tau Pathology in Alzheimer's Disease. Sánchez-Aced, É, Moya-Llamas, B, Aumatell Escabias, J et al. Neuropathol Appl Neurobiol 2025PMID:40025904
- Evaluation of cerebrospinal fluid levels of VAMP-2 and SNAP-25 in a dementia with Lewy bodies clinical cohort stratified by Alzheimer's pathophysiological biomarkers. González, AC, Goossens, J, Campuzano, EV et al. Alzheimers Res Ther 2025PMID:39994784
- Dissociating language switching from executive control in bilinguals with MCI. Calabria, M, Suades, A, Juncadella, M et al. Cortex 2025PMID:39765077
- Posterior Cortical Atrophy Due to Alzheimer Disease in a Person With Down Syndrome: A Case Report. Rodríguez-Baz, Í, Benejam, B, Morcillo-Nieto, AO et al. Neurology 2025PMID:39689339
- New treatments in Alzheimer's disease. Lleó, A Med Clin (Barc) 2025PMID:39616028
- Amyloid-lowering treatment in Alzheimer's disease. Jessen, F, Frölich, L, Hort, J et al. Lancet 2024PMID:39551061
- What Can We Learn About Alzheimer's Disease from People with Down Syndrome?. Maure-Blesa, L, Rodríguez-Baz, I, Carmona-Iragui, M et al. Curr Top Behav Neurosci 2025PMID:39509049
- Challenges in the practical implementation of blood biomarkers for Alzheimer's disease. Schöll, M, Verberk, IMW, Del Campo, M et al. Lancet Healthy Longev 2024PMID:39369727
- Context matters: the evolving use of biomarkers in Alzheimer's disease care. Fortea, J EBioMedicine 2024PMID:39366842
- Characterization of white matter hyperintensities in Down syndrome. Morcillo-Nieto, AO, Zsadanyi, SE, Arriola-Infante, JE et al. Alzheimers Dement 2024PMID:39087352
- Associations of Microbleeds and Their Topography With Imaging and CSF Biomarkers of Alzheimer Pathology in Individuals With Down Syndrome. Zsadanyi, SE, Morcillo-Nieto, AO, Aranha, MR et al. Neurology 2024PMID:39074338
- Correction: Diagnostic performance of plasma pTau217, pTau181, Aβ1‑42 and Aβ1‑40 in the LUMIPULSE automated platform for the detection of Alzheimer disease. Arranz, J, Zhu, N, Rubio-Guerra, S et al. Alzheimers Res Ther 2024PMID:39068457
- APP dyshomeostasis in the pathogenesis of Alzheimer's disease: implications for current drug targets. Sirisi, S, Sánchez-Aced, É, Belbin, O et al. Alzheimers Res Ther 2024PMID:38951839
- Diagnostic performance of plasma pTau217, pTau181, Aβ1-42 and Aβ1-40 in the LUMIPULSE automated platform for the detection of Alzheimer disease. Arranz, J, Zhu, N, Rubio-Guerra, S et al. Alzheimers Res Ther 2024PMID:38926773
- Occurrence of mosaic Down syndrome and prevalence of co-occurring conditions in Medicaid enrolled adults, 2016-2019. Rubenstein, E, Tewolde, S, Skotko, BG et al. Am J Med Genet C Semin Med Genet 2024PMID:38925597
- What Can Blood Biomarkers Tell Us About Patients With Lewy Body Dementia?. Lleó, A, Alcolea, D Neurology 2024PMID:38830183
- Cortical microinfarcts in adults with Down syndrome assessed with 3T-MRI. Aranha, MR, Montal, V, van den Brink, H et al. Alzheimers Dement 2024PMID:38644660
- Diagnostic performance of plasma pTau 217, pTau 181, Aβ 1-42 and Aβ 1-40 in the LUMIPULSE automated platform for the detection of Alzheimer disease. Arranz, J, Zhu, N, Rubio-Guerra, S et al. Res Sq 2023PMID:38168408
- Down Syndrome in a New Era for Alzheimer Disease. Rafii, MS, Fortea, J JAMA 2023PMID:37991807
- Clinical dimensions along the non-fluent variant primary progressive aphasia spectrum. Illán-Gala, I, Lorca-Puls, DL, Tee, BL et al. Brain 2024PMID:37988272
- Bilingual Primary Progressive Aphasia: A Scoping Review of Assessment and Treatment Practices. Grasso, SM, Wagner Rodríguez, CA, Montagut Colomer, N et al. J Alzheimers Dis 2023PMID:37980666