Publicaciones recientes

Lista de publicaciones más recientes lideradas por la Unidad de Memoria del Hospital de Sant Pau:

  1. Cognitive functioning as an underutilized determinant of treatment planning: a review in alcohol use disorder. Streel, E, Jones, M, Iulita, MF et al. Front Psychol 2026
    PMID:42774887

  2. Changes in serum β-synuclein precede blood biomarkers of Alzheimer pathology in Down syndrome. Cervantes González, A, Morcillo-Nieto, AO, Serrano, S et al. Alzheimers Dement 2026
    PMID:42768868

  3. A scalable workflow using digital cognitive assessment and pTau217 for MCI detection. Vairavan, S, Griffin, N, Wilson, D et al. Alzheimers Dement (Amst) 2026
    PMID:42757183

  4. Natural history and clinical impact of epilepsy in adults with Down syndrome: a multicentre clinical study. Maure-Blesa, L, Carmona-Iragui, M, Barroeta, I et al. Lancet 2026
    PMID:42692040

  5. Pre-dementia clinical trajectories associated with neuronal α-synuclein neuropathologic change: a retrospective cohort study. Vera-Campuzano, E, Selma-González, J, Rodríguez-Baz, Í et al. Res Sq 2026
    PMID:42687952

  6. Semantic control across Alzheimer's disease phenotypes: cognitive mechanisms and neural correlates. Armas, P, Morcillo-Nieto, AO, Zsadanyi, SE et al. Front Aging Neurosci 2026
    PMID:42656695

  7. The predictive power of neuropsychological measures in MCI: early detection of dementia conversion. Padilla, C, Zsadanyi, SE, Aragón, I et al. Front Aging Neurosci 2026
    PMID:42404240

  8. Clinical Impact and Prognostic Value of Alzheimer Disease Biomarkers in the Very Old. Ceriello, C, Torres, OH, Rubio-Guerra, S et al. Neurology 2026
    PMID:42308436

  9. Peak width of skeletonized mean diffusivity reveals early and multifactorial white matter injury across sporadic and Down syndrome-associated Alzheimer's disease. Morcillo-Nieto, AO, Franquesa-Mullerat, M, Zsadanyi, SE et al. Alzheimers Dement 2026
    PMID:42212383

  10. A Clinician View of the EMA Explanation of the Approval of Amyloid-Targeting Therapies. Jessen, F, Fortea, J Lancet Reg Health Eur 2026
    PMID:42180984

  11. Characterizing circadian rest-activity rhythm patterns across Alzheimer's disease continuum in Down syndrome. Giménez, S, Vaqué-Alcázar, L, Clos, S et al. Alzheimers Dement 2026
    PMID:42056071

  12. Evidence for bilingualism as a cognitive reserve factor in biomarker-confirmed Alzheimer's disease. Grasso, SM, Bao, W, Marqués-Kiderle, SK et al. medRxiv 2026
    PMID:41959833

  13. Amyloid-linked versus age-driven copathologies in Alzheimer's dementia: differential associations with APOE ε4. Rodríguez-Baz, Í, Vaqué-Alcázar, L, Maure-Blesa, L et al. Res Sq 2026
    PMID:41890856

  14. Impaired semantic word learning in primary progressive aphasia. Olivé, G, Cardona, G, Porto, MF et al. Brain Struct Funct 2026
    PMID:41882244

  15. Temporal dynamics of white matter hyperintensities related to Alzheimer's disease in adults with Down syndrome. Morcillo-Nieto, AO, Rozalem-Aranha, M, Maure-Blesa, L et al. Alzheimers Dement 2026
    PMID:41639041

  16. Potential role of MRI to optimize clinical trial design for progressive supranuclear palsy and corticobasal degeneration. García-Castro, J, VandeVrede, L, Donohue, MC et al. J Prev Alzheimers Dis 2026
    PMID:41581260

  17. Development of amyloid-negative neuropsychological norms using GAMLSS. Rubio-Guerra, S, Sánchez-Saudinós, MB, Sala, I et al. Alzheimers Dement (Amst) 2025
    PMID:41383879

  18. Amyloid-negative neuropsychological norms: Added value in the era of biomarkers and disease-modifying therapies. Rubio-Guerra, S, Sala, I, Sánchez-Saudinós, MB et al. Alzheimers Dement (Amst) 2025
    PMID:41383878

  19. Sleep-related changes in astrocytic biomarkers are modulated by APOE ε4 genotype in cognitively unimpaired adults. Zhu, N, Altuna, M, Arranz, J et al. Brain Commun 2025
    PMID:41268178

  20. Generational effects in Down syndrome: Enriched environment enhances functionality without reducing Alzheimer's disease risk. Vaqué-Alcázar, L, Videla, L, Benejam, B et al. Alzheimers Dement 2025
    PMID:41041908

  21. Study of brain perfusion in adults with Down syndrome along the Alzheimer's disease continuum. Franquesa-Mullerat, M, Morcillo-Nieto, AO, Arriola-Infante, JE et al. Alzheimers Dement 2025
    PMID:40968330

  22. Prospective evaluation of plasma pTau217 stability for the detection of Alzheimer's disease in a tertiary memory clinic. Arranz, J, Ferrer, R, Zhu, N et al. Alzheimers Res Ther 2025
    PMID:40618130

  23. Impact of Alzheimer's disease on sleep in adults with Down syndrome. Giménez, S, Vaqué-Alcázar, L, Zhu, N et al. Alzheimers Dement 2025
    PMID:40604343

  24. Discrepancies in assessing intellectual disability levels in adults with Down syndrome: Implications for dementia diagnosis. Soriano, LDH, Sandkühler, K, Videla, L et al. Alzheimers Dement 2025
    PMID:40528393

  25. The Down Alzheimer Barcelona Neuroimaging Initiative (DABNI) and its contributions to understanding Alzheimer's disease in Down syndrome: A decade of discovery. Videla, L, Benejam, B, Barroeta, I et al. Alzheimers Dement 2025
    PMID:40528282

  26. Cargo of small extracellular vesicles from neuronal origin shows progression of dementia in individuals with Down syndrome. Ledreux, A, Carmona-Iragui, M, Videla, L et al. Alzheimers Dement 2025
    PMID:40524460

  27. Association of Plasma Phosphorylated Tau 217 With Clinical Deterioration Across Alzheimer Disease Stages. Selma-Gonzalez, J, Rubio-Guerra, S, García-Castro, J et al. Neurology 2025
    PMID:40472304

  28. The history of Down syndrome-associated Alzheimer's disease; past, present, and future. Maure-Blesa, L, Carmona-Iragui, M, Lott, I et al. Alzheimers Dement 2025
    PMID:40469048

  29. Sex differences in the executive and behavioral reserve of autosomal dominant frontotemporal dementia. Garcia Castro, J, Rubio-Guerra, S, Casaletto, KB et al. Alzheimers Dement 2025
    PMID:40277045

  30. Nerve growth factor precursor alterations in neuron-derived extracellular vesicles from individuals with Down syndrome along the Alzheimer's disease continuum. Valle-Tamayo, N, Aranha, MR, Pérez-González, R et al. Alzheimers Dement 2025
    PMID:40257051

  31. A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration. Rubio-Guerra, S, Bernal, S, Almenta, D et al. Ann Clin Transl Neurol 2025
    PMID:40244880

  32. Medial temporal lobe atrophy in Down syndrome along the Alzheimer's disease continuum. Buehner, BJ, Morcillo-Nieto, AO, Zsadanyi, SE et al. Brain 2025
    PMID:40243675

  33. Sex-related differences in genetically determined Alzheimer's disease. Del Hoyo Soriano, L, Wagemann, O, Bejanin, A et al. Front Aging Neurosci 2025
    PMID:40103931

  34. Regional Brain Metabolism across the Alzheimer's Disease Continuum in Down Syndrome. Arriola-Infante, JE, Morcillo-Nieto, AO, Zsadanyi, SE et al. Ann Neurol 2025
    PMID:40084922

  35. Enhancing Lateral Resolution Using Two-Colour Direct Stochastic Optical Reconstruction Microscopy to Unravel Synaptic Tau Pathology in Alzheimer's Disease. Sánchez-Aced, É, Moya-Llamas, B, Aumatell Escabias, J et al. Neuropathol Appl Neurobiol 2025
    PMID:40025904

  36. Evaluation of cerebrospinal fluid levels of VAMP-2 and SNAP-25 in a dementia with Lewy bodies clinical cohort stratified by Alzheimer's pathophysiological biomarkers. González, AC, Goossens, J, Campuzano, EV et al. Alzheimers Res Ther 2025
    PMID:39994784

  37. Dissociating language switching from executive control in bilinguals with MCI. Calabria, M, Suades, A, Juncadella, M et al. Cortex 2025
    PMID:39765077

  38. Posterior Cortical Atrophy Due to Alzheimer Disease in a Person With Down Syndrome: A Case Report. Rodríguez-Baz, Í, Benejam, B, Morcillo-Nieto, AO et al. Neurology 2025
    PMID:39689339

  39. New treatments in Alzheimer's disease. Lleó, A Med Clin (Barc) 2025
    PMID:39616028

  40. Amyloid-lowering treatment in Alzheimer's disease. Jessen, F, Frölich, L, Hort, J et al. Lancet 2024
    PMID:39551061

  41. What Can We Learn About Alzheimer's Disease from People with Down Syndrome?. Maure-Blesa, L, Rodríguez-Baz, I, Carmona-Iragui, M et al. Curr Top Behav Neurosci 2025
    PMID:39509049

  42. Challenges in the practical implementation of blood biomarkers for Alzheimer's disease. Schöll, M, Verberk, IMW, Del Campo, M et al. Lancet Healthy Longev 2024
    PMID:39369727

  43. Clinical and research application of fluid biomarkers in autosomal dominant Alzheimer's disease and Down syndrome. Carmona-Iragui, M, O'Connor, A, Llibre-Guerra, J et al. EBioMedicine 2024
    PMID:39366843

  44. Context matters: the evolving use of biomarkers in Alzheimer's disease care. Fortea, J EBioMedicine 2024
    PMID:39366842

  45. Characterization of white matter hyperintensities in Down syndrome. Morcillo-Nieto, AO, Zsadanyi, SE, Arriola-Infante, JE et al. Alzheimers Dement 2024
    PMID:39087352

  46. Associations of Microbleeds and Their Topography With Imaging and CSF Biomarkers of Alzheimer Pathology in Individuals With Down Syndrome. Zsadanyi, SE, Morcillo-Nieto, AO, Aranha, MR et al. Neurology 2024
    PMID:39074338

  47. Correction: Diagnostic performance of plasma pTau217, pTau181, Aβ1‑42 and Aβ1‑40 in the LUMIPULSE automated platform for the detection of Alzheimer disease. Arranz, J, Zhu, N, Rubio-Guerra, S et al. Alzheimers Res Ther 2024
    PMID:39068457

  48. APP dyshomeostasis in the pathogenesis of Alzheimer's disease: implications for current drug targets. Sirisi, S, Sánchez-Aced, É, Belbin, O et al. Alzheimers Res Ther 2024
    PMID:38951839

  49. Diagnostic performance of plasma pTau217, pTau181, Aβ1-42 and Aβ1-40 in the LUMIPULSE automated platform for the detection of Alzheimer disease. Arranz, J, Zhu, N, Rubio-Guerra, S et al. Alzheimers Res Ther 2024
    PMID:38926773

  50. Occurrence of mosaic Down syndrome and prevalence of co-occurring conditions in Medicaid enrolled adults, 2016-2019. Rubenstein, E, Tewolde, S, Skotko, BG et al. Am J Med Genet C Semin Med Genet 2024
    PMID:38925597

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